Tear Trough Deformity: Review of Anatomy and Treatment Options

The lower eyelid can be a challenging area in facial rejuvenation, especially when patients present with tear trough deformity. In this CME article, the authors outline our current understanding of the tear trough anatomy, describe multiple classification systems, and review both surgical and nonsurgical techniques for treatment.

A Novel Prospective Three-Dimensional Analysis of Nasolabial Fold Augmentation

Armando A. Davila, BS; Donald W. Buck II, MD; David Chopp, PhD; Caitlin M. Connor, BA; Scott Persing, BA, MPH; Vinay Rawlani, MD; and John Y. S. Kim, MD

The authors report on a mathematical model validated in a small series of patients to analyze three-dimensional (3D) volumetric changes after human acellular dermis (HADM) nasolabial fold augmentation.

Comparison of Five Commonly-Available, Lidocaine-Containing Topical Anesthetics and Their Effect on Serum Levels of Lidocaine and Its Metabolite Monoethylglycinexylidide (MEGX)

Georgette Oni, MBChB, MRCS; Spencer Brown, PhD; and Jeffrey Kenkel, MD, FACS

In this ASERF-funded study, the authors compare five commonly-available lidocaine preparations and their levels of systemic absorption when applied to the face. Serum levels were determined by blood drawn at several time points, up to eight hours after treatment.

Equivalent Effects of Topically-Delivered Adipose-Derived Stem Cells and Dermal Fibroblasts in the Ischemic Rabbit Ear Model for Chronic Wounds

Mesenchymal stem cells (MSC) have garnered considerable attention because both MSC and their adipose-derived counterparts (ADSC) have been suggested to stimulate cutaneous wound healing. In this report, the authors evaluate the role of MSC in an ischemic variant of their well-established rabbit ear model.